A Review on Cryptorchidism-Induced Alopecia in Dogs

Kanchan  Walwadkar; Shilpa  Gajbhiye; Saurabh  Banerjee; Apurv  Kaushik

doi:10.69968/ijisem.2025v4i2181-185

Authors

Kanchan Walwadkar Assistant Professor, College of Veterinary Sci and A.H., Rewa, M.P.
Shilpa Gajbhiye Assistant Professor, College of Veterinary Sci and A.H., Jabalpur, M.P.
Saurabh Banerjee Veterinary Assistant Surgeon, Baikuntthpur, Livestock Development Department, Chhattisgarh.
Apurv Kaushik Assistant Professor, RPS College of Veterinary Sci. and A.H., Mahendergarh

DOI:

https://doi.org/10.69968/ijisem.2025v4i2181-185

Keywords:

Cryptorchidism, Alopecia, Dog, Neoplastic risks, Diagnosis, Cryptorchid dogs

Abstract

A disorder known as cryptorchidism occurs when a single or both testicles are unable to descend into the scrotum from the belly. Alopecia is among the most prevalent dermatological conditions. The literature on alopecia in dogs caused by cryptorchidism is reviewed in this article. It concluded that cryptorchidism in dog’s presents with variable anatomical patterns across breeds and contributes to fertility issues and increased neoplastic risks due to altered seminiferous epithelium. Ultrasonography remains the gold standard for diagnosis, while surgical removal of both retained and descended testes is essential. Additionally, cryptorchidism may be associated with dermatological manifestations such as alopecia areata-like disease, with cyclosporine showing partial efficacy. These findings highlight the importance of early diagnosis and comprehensive clinical management of cryptorchid dogs.

References

[1] M. Siam, A. E.-K. R. E.- Sheikh, and N. E. Attia, "Alopecia in dogs: causes, incidance and clinical signs with special reference to nutritional alopecia," Zagazig Vet. J., vol. 50, no. 2, pp. 136-147, 2022,https://doi.org/10.21608/zvjz.2022.125735.1175

[2] I. Szczerbal and M. Switonski, "Clinical cytogenetics of the dog: A review," Animals, vol. 11, no. 4, pp. 1-15, 2021,https://doi.org/10.3390/ani11040947

[3] V. Bhuvaneshwari and M. M. Begum, "Surgical management of cryptorchidism in beagle dogs - A report of 7 cases," Indian Vet. J., vol. 95, no. 8, pp. 82-83, 2018.

[4] A. I. Kisani et al., "Sertoli cell tumor in a cryptorchid dog," J. Adv. Vet. Anim. Res., vol. 4, no. 4, pp. 394-398, 2017,https://doi.org/10.5455/javar.2017.d237

[5] A. Bufalari, A. Proni, G. Moretti, A. Di Meo, and S. Pirico, "The lameness in a cryptorchid dog with intra-abdominal torsion of one of the two neoplastic testicles: A case report," Vet. Med. (Praha)., vol. 60, no. 8, pp. 456-459, 2015,https://doi.org/10.17221/8421-VETMED

[6] S. M. Cutler, M. Melega, L. Wilson, C. R. Breheny, and J. C. Serra, "Utility of preputial cytology to diagnose hyperoestrogenism in a dog with an intra-abdominal Sertoli cell tumour with concurrent thrombocytopaenia and intracranial haemorrhage," Vet. Rec. Case Reports, vol. 10, no. 1, 2022,https://doi.org/10.1002/vrc2.245

[7] A. Fang, L. Kumar, K. E. Creevy, D. E. L. Promislow, and J. Ma, "The first comorbidity networks in companion dogs in the Dog Aging Project," 2024.https://doi.org/10.1101/2024.12.18.629088

[8] D. W. Song et al., "Testosterone/estradiol ratio in a dog with sertoli cell tumor-seminoma combination," J. Vet. Clin. vol. 38, no. 5, pp. 221-224, 2021,https://doi.org/10.17555/jvc.2021.38.5.221

[9] C. R. Sanz, J. Sarquis, M. Á. Daza, and G. Miró, "Exploring the impact of epidemiological and clinical factors on the progression of canine leishmaniosis by statistical and whole genome analyses: from breed predisposition to comorbidities," Int. J. Parasitol., vol. 54, no. 8-9, pp. 401-414, 2024,https://doi.org/10.1016/j.ijpara.2024.03.006

[10] S. Stokowski, J. Ruth, O. Lanz, and V. Ziglioli, "Computed tomographic features in a case of Bilateral Neoplastic cryptorchidism with suspected torsion in a dog," Front. Vet. Sci., vol. 3, no. APR, pp. 1-5, 2016,https://doi.org/10.3389/fvets.2016.00033

[11] H. H. L. Nascimento et al., "Testicular tumors in 190 dogs: clinical, macroscopic and histopathological aspects1," Pesqui. Vet. Bras. vol. 40, no. 7, pp. 525-535, 2020,https://doi.org/10.1590/1678-5150-pvb-6615

[12] S. E. Cho, J. M. Fudge, S. Kim, B. Page, and D. H. Yu, "Cryptorchidism in dogs and cats presented for elective gonadectomy: A descriptive cohort study of 306 animals treated between 2018 and 2023," Top. Companion Anim. Med., vol. 65, no. March 2018, p. 100961, 2025,https://doi.org/10.1016/j.tcam.2025.100961

[13] S. L. Devi, R. Ravi, D. Gopikrishnan, D. Sumathi, and S. Meharaj, "Prostatic abscess and feminization associated with bilateral seminoma in a cryptorchid dog," Int. J. Vet. Sci. Anim. Husb., vol. 9, no. 3, pp. 119-122, 2024.

[14] N. Hernández-Jardón et al., "Cryptorchidism: The dog as a study model," Front. Vet. Sci., vol. 9, 2022,https://doi.org/10.3389/fvets.2022.935307

[15] J. SPASOJEVIĆ et al., "Cryptorchidism in dogs.," Vet. J. Repub. Srp. (Banja Luka), vol. 22, no. 1-2, 2022,https://doi.org/10.7251/VETJEN2201142S

[16] C. Spangenberg, "Canine Cryptorchidism: A Concise Review of its Origin, Diagnosis and Treatment Caroline Spangenberg," Biol. Eng. Med. Sci. Reports, vol. 7, no. 1, pp. 1-3, 2021,https://doi.org/10.5530/bems.7.1.1

[17] F. Scarampella and P. Roccabianca, "Alopecia areata in a dog: Clinical, dermoscopic and histological features," Ski. Appendage Disord., vol. 4, no. 2, pp. 112-117, 2018,https://doi.org/10.1159/000479781

[18] Surya Pratap Singh et al. 2023. Artificial Intelligence and Machine Learning-Based Approaches for Neurodegenerative Diseases Diagnosis. International Journal of Innovations in Science, Engineering And Management. 2, 4 (Nov. 2023), 31-37.