Phytochemical and anti hyperlipidemic activity of leaves extract of lagerstromia microcarpa
DOI:
https://doi.org/10.69968/ijisem.2025v4i2390-395Keywords:
Antihyperlipidemia activity, Lagerstromia microcarpa, triglycerides, total cholesterolAbstract
The present study investigated the phytochemicals and in-vivo anti hyperlipidimic activity of hydroalcoholic extract of leaves of lagerstroemia microcarpa wight. According to phytochemical study, the plant contains a variety of secondary metabolites with pharmacologically significant qualities, including flavonoids, phenol, saponins, proteins, carbohydrates, and alkaloids. Hyperlipidaemia induced by the diet was significantly reduced in rodents by the hydroalcoholic extract. In a dose-dependent manner, all treatment groups led to a substantial reduction in "serum levels of total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), very low density lipoprotein cholesterol (VLDL-C), and high density lipoprotein cholesterol (HDL-C)", which was comparable to the standard drug Atorvastatin. In addition, "the hydroalcoholic extract of Lagerstroemia microcarpa leaves extract (300mg/kg)" significantly reduced serum LDL-C levels.
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